2024

・K. Nishimura, X. Huang, A. Yoshinaga-Kiriake, Y. Yahata, S. Tanaka, N. Gotoh, and K. Yoshinaga. Formation of epoxy fatty acids in triacylglycerol standards during heating. J. Oleo Sci. in press.

・H. Shikano, K. Matsumoto, F. Honma, N. Obana, K. Yoshinaga, Y. Takada, N. Ishikawa, M. Hara, and S. Taira. Determination and imaging of lactones in beef by Girard’s reagent T derivatization technique. Sens. Meter. in press.

・A. Yoshinaga-Kiriake, K. Yoshinaga, S. Miyagawa, K. Yoshino, S. Tanaka, T. Takahashi, S. Kato, J. Ito, Y. Otoki, K. Nakagawa, and N. Gotoh. Comparison of the catabolic rates of linoleic and oleic acid hydroperoxides using 13CO2 expired from mice. J. Oleo Sci. in press.

2023

・吉永 和明. 乳脂肪におけるラクトン光学異性体の分布, ミルクサイエンス 72, 113-119 (2023). [Abstract]

2022

・K. Yoshinaga, K. Yamazaki, T. Nagai, S. Tanaka, and N. Gotoh. Stable isotope tracer to reveal the interconversion between 3-monochloro-1,2-propanediol ester and glycidyl ester during the deodorization process. J. Agri. Food Chem. 70, 15955-15961 (2022). [Abstract]

・A. Yoshinaga-Kiriake, D. Takata, T. Norito, M. Maki, S. Mochizuki, and K. Yoshinaga. Comparative evaluation of fatty acid composition, tocopherols, and volatile compounds of walnut oil between Juglans mandshurica Maxim. var. sachalinensis (Komatsu) Kitam and J. regia L. J. Oleo Sci. 71, 1743-1748 (2022). [Paper (pdf)]

・A. Nakamura, C. Ishii, K. Yoshinaga, T. Kuda, and H. Takahashi. Growth inhibition of Listeria monocytogenes in fresh white cheese by mustard oil microemulsion. J. Food Prot. 85, 1404-1409 (2022). [Abstract]

・T. Takahashi, S. Kato, J. Ito, N. Shimizu, I. S. Parida, M. Sakaino, J. Imagi, K. Yoshinaga, A. Yoshinaga-Kiriake, N. Gotoh, I. Ikeda, and K. Nakagawa. Dietary triacylglycerol hydroperoxide is not absorbed, yet it induces the formation of other triacylglycerol hydroperoxides in the gastrointestinal tract. Redox Biol. 57, 102471 (2022). [Paper (pdf)]

・R. Saeki, K. Yoshinaga, A. Tago, S. Tanaka, A. Yoshinaga-Kiriake, T. Nagai, A. Yoshida, and N. Gotoh. Quantitative analysis of lactone enantiomers in butter and margarine through the combination of solvent extraction and enantioselective gas chromatography-mass spectrometry. J. Agri. Food Chem. 70, 5756-5763 (2022). [Abstract]

・ K. Nagao, J. Ueno, K. Yoshinaga, T. Nagai, H. Mizobe, A. Yoshida, F. Beppu, S. Tanaka, and N. Gotoh. Comparison of lipoprotein cholesterol levels in golden Syrian hamster administrated trans-octadecenoic acid positional isomers. J. Oleo Sci. 71, 609-618 (2021). [Paper (pdf)]

・ K. Yoshinaga, Y. Usami, A. Yoshinaga-Kiriake, H. Shikano, S. Taira, R. Nagasaka, S. Tanaka, and N. Gotoh. Visualization of dietary docosahexaenoic acid in whole-body zebrafish using matrix-assisted laser desorption/ionization mass spectrometry imaging. J. Nutr. Biochem. 100, 108897 (2022). [Abstract]

2021

・ K. Yoshinaga, H. Ishikawa, F. Beppu, and N. Gotoh. Incorporation of dietary arachidonic and docosatetraenoic acid into mouse brain. J. Agri. Food Chem. 69, 2457-2461 (2021). [Abstract]

・ K. Yoshinaga, Y. Mizuno, S. Senarath, A. Yoshinaga-Kiriake, T. Nagai, F. Beppu, S. Tanaka, and N. Gotoh. Simultaneous treatment of long-chain monounsaturated fatty acid and n-3 polyunsaturated fatty acid decreases lipid and cholesterol levels in HepG2 cell. J. Oleo Sci. 70, 731-736 (2021). [Paper (pdf)]

・ S. Taira, A. Kiriake-Yoshinaga, H. Shikano, R. Ikeda, S. Kobayashi, and K. Yoshinaga. Localization analysis of essential oils in perilla herb (Perilla frutescens var. crispa) using derivatized mass spectrometry imaging. Food. Sci. Nutr. 9, 2779-2784 (2021). [Paper (pdf)]

・ K. Yoshinaga, A. Tago, A. Yoshinaga-Kiriake, and N. Gotoh. Characterization of lactones in Wagyu (Japanese beef) and imported beef by combining solvent extraction and gas chromatography–mass spectrometry. LWT. 135, 110015 (2021). [Paper (pdf)]

・ K. Yoshinaga. Development of analytical methods and nutritional studies using synthetic fatty acids and triacylglycerols. J. Oleo Sci. 70, 1-9 (2021). [Paper (pdf)]

・ 西村 順子,吉永 和明, 松田 幹. 乳業用スターターを用いて製造した発酵バター様乳製品の揮発性化合物, ミルクサイエンス 70, 139-145 (2021). [Abstract]

・ 吉永 和明. 食事由来多価不飽和脂肪酸の脳内動態の可視化, アグリバイオ 5, 516-520 (2021). 

2020

・ T. Nagai, T. Kinoshita, E. Kasamatsu, K. Yoshinaga, H. Mizobe, A. Yoshida, Y. Itabashi, and N. Gotoh. Simultaneous quantification of mixed-acid triacylglycerol positional isomers and enantiomers in palm oil and lard by chiral high-performance liquid chromatography coupled with mass spectrometry. Symmetry 12, 1385 (2020). [Article]

・ A. Yoshinaga-Kiriake, K. Yoshinaga, and N. Gotoh. Effect of trans-octadecenoic acid positional isomers on tumor necrosis factor-α secretion in RAW264.7 cells. J. Oleo Sci. 691139-1143 (2020). [Paper (pdf)]

・ H. Shikano, Y. Miyama, R. Ikeda, T. Haga, J. Suda, K. Yoshinaga, and S. Taira. Localization analysis of multiple vitamins in dried persimmon (Diospyros kaki) using matrix-assisted laser desorption ionization mass spectrometry imaging. J. Oleo Sci. 69959-964 (2020). [Paper (pdf)]

・ K. Yoshinaga, H. Ishikawa, S. Taira, A. Yoshinaga-Kiriake, Y. Usami, and N. Gotoh. Selective visualization of administrated arachidonic and docosahexaenoic acids in brain using combination of simple stable isotope-labeling technique and imaging mass spectrometry. Anal. Chem. 92, 8685-8690 (2020). [Abstract]

2019

・ K. Yoshinaga, A. Tago, A. Yoshinaga-Kiriake, T. Nagai, A. Yoshida, and N. Gotoh. Effects of heat treatment on lactone content of butter and margarine. J. Oleo Sci. 68, 1295-1301 (2019). [Paper (pdf)]

・ K. Yoshinaga, F. Beppu, Y Yamatani, A. Kubo, A. Yoshinaga-Kiriake, T. Nagai, A. Yoshida, J. Kanda, and N. Gotoh, Effect of calcium treatment on catabolic rates of 13C-labeled fatty acids bound to the α and β positions of triacylglycerol. J. Oleo Sci. 68, 1149-1155 (2019). [Paper (pdf)]

・ T. Nagai, T. Kinoshita, E. Kasamatsu, Y. Kazuaki, H. Mizobe, A. Yoshida, Y. Itabashi, and N. Gotoh. Simultaneous separation of triacylglycerol enantiomers and positional isomers by chiral high performance liquid chromatography coupled with mass spectrometry. J. Oleo Sci. 68, 1019-1026 (2019). [Paper (pdf)]

・ K. Yoshinaga, F. Beppu, Y. Yamatani, A. Kubo, A. Yoshinaga-Kiriake, T. Nagai, A. Yoshida, J. Kanda, and N. Gotoh. Examination of 13C-labeled fatty acid catabolic rates bound to the α and β positions of triacylglycerol using 13CO2 expired from mice. J. Oleo Sci. 68591-598 (2019). [Paper (pdf)]

・ S. Senarath, F. Beppu, K. Yoshinaga, T. Nagai, A. Yoshida, and N. Gotoh. Comparison of the effect of long chain monounsaturated fatty acids positional isomers on lipid metabolism in 3T3-L1 cells. J. Oleo Sci. 68379-387 (2019). [Paper (pdf)]

・ K. Vriens, S. Christen, S. Parik, D. Broekaert, K. Yoshinaga, A. Talebi, J. Dehairs, C. Escalona-Noguero, R. Schmieder, T. Cornfield, C. Charlton, L. Romero-Perez, M. Rossi, G. Rinaldi, M. F. Orth, R. Boon, A. Kerstens, S. Y. Kwan, B. Faubert, A. Mendez-Lucas, C. C. Kopitz, T. Chen, J. Fernandez-Garcia, J. A. G. Duarte, A. Schmitz, P. Steigemann, M. Najimi, A. Hagebarth, J. A. Van Ginderachter, E. Sokal, N. Gotoh, K. Wong, C. Verfaillie, R. Derua, S. Munck, M. Yuneva, L. Beretta, R. J. DeBerardinis, J. V. Swinnen, L. Hodson, D. Cassiman, C. Verslype, S. Christian, S. Grunewald, T. G. P. Grunewald, and S. Fendt. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature 566, 403-406 (2019). [Abstract] [Japanese Abstract]

・ N. Gotoh, K. Yoshinaga, S. Kagiono, Y. Katoh, Y. Mizuno, F. Beppu, T. Nagai, H. Mizobe, A. Yoshida, and K. Nagao. Evaluating the content and distribution of trans fatty acid isomers in foods consumed in Japan. J. Oleo Sci. 68193-202 (2019). [Paper (pdf)]

・ K. Yoshinaga, J. Obi, A. Tago, Y. Kato, T. Nagai, A. Yoshida, and N. Gotoh. Analysis of hydroxy triacylglycerol as a lactone precursor in milk fat using liquid chromatography electrospray ionization tandem mass spectrometry. Food Chem. 274, 298-304 (2019). [Abstract]

・ 吉永 和明.【総説】GCによるトリアシルグリセロール分子種およびラクトン類の分析, オレオサイエンス 19, 497-505 (2019). [Review (pdf)]

2018

・ N. Gotoh, K. Nagao, H. Ishida, K. Nakamitsu, K. Yoshinaga, T. Nagai, F. Beppu, A. Yoshinaga-Kiriake, H. Watanabe, and T. Yanagita. Metabolism of natural highly unsaturated fatty acid, tetracosahexaenoic acid (24:6n-3), in C57BL/KsJ-db/db mice. J. Oleo Sci. 67 1597-1607 (2018). [Paper (pdf)]

・ J. Obi, K. Yoshinaga, A. Tago, T. Nagai, A. Yoshida, F. Beppu, and N. Gotoh. Simple quantification of lactones in milk fat by solvent extraction using gas chromatography-mass spectrometry. J. Oleo Sci. 67941-948 (2018). [Paper (pdf)]

・ S. Senarath, K. Yoshinaga, T. Nagai, A. Yoshida, F. Beppu, and N. Gotoh, Differential effect of cis-eicosenoic acid positional isomers on adipogenesis and lipogenesis in 3T3-L1 cells.  Eur. J. Lipid Sci. Technol. 1700512 (2018). [Abstract]

・ N. Gotoh, S. Kagiono, K. Yoshinaga, H. Mizobe, T. Nagai, A. Yoshida, F. Beppu, and K. Nagao. Study on the trans fatty acid formation in oil by heating using model compounds. J. Oleo Sci. 67273-281 (2018)[Paper (pdf)]

2017

・ T. Nagai, K Ishikawa, K. Yoshinaga, A. Yoshida, F. Beppu, and N. Gotoh. Homochiral asymmetric triacylglycerol isomers in egg yolk. J. Oleo Sci. 661293-1299 (2017)[Paper (pdf)]

・ K. Nagao, K. Yoshinaga, T. Nagai, H. Mizobe, A. Yoshida, F. Beppu, and N. Gotoh, Comparison of the effect on apolipoprotein A1 and B secretion among trans fatty acid isomers using HepG2 cell. J. Oleo Sci. 661175-1181 (2017)[Paper (pdf)]

・ F. Beppu, H. Li, K. Yoshinaga, T. Nagai, A. Yoshinda, A. Kubo, J. Kanda, and N. Gotoh. Dietary starfish oil prevents hepatic steatosis and hyperlipidemia in C57BL/6N mice fed high-fat diet. J. Oleo Sci. 66761-769 (2017)[Paper (pdf)]

・ K. Yoshinaga, J. Obi, T. Nagai, H. Iioka, A. Yoshida, F. Beppu, and N. Gotoh. Quantification of triacylglycerol molecular species in edible fats and oils by gas chromatography-flame ionization detector using correction factors. J. Oleo Sci. 66, 259-268 (2017). [Paper (pdf)]

・ S. Senarath, K. Yoshinaga, T. Nagai, A. Yoshida, F. Beppu, C. Jayasinghe, C. Devadawsond, and N. Gotoh. Quantitative analysis of distribution of cis-eicosenoic acid positional isomers in marine fish from the Indian Ocean. J. Oleo Sci. 66, 187-197 (2017). [Paper (pdf)]

・ F. Beppu, T. Kawamatsu, Y. Yamatani, T. Nagai, K. Yoshinaga, H. Mizobe, A. Yoshida, A. Kubo, J. Kanda, and N. Gotoh. Comparison of 13C-labeled fatty acid catabolic rates bound to the sn-1, sn-2, and sn-3 positions of triacylglycerol using 13C-labeled CO2 expired from mice. J. Oleo Sci. 66, 85-91 (2017). [Paper (pdf)]

2016

・ N. Watanabe, T. Nagai, H. Mizobe, K. Yoshinaga, A. Yoshida, Y. Kitamura, T. Shimizu, F. Beppu, and N. Gotoh. Quantification of triacylglycerol positional isomers in rat milk. J. Oleo Sci. 65, 977-983 (2016). [Paper (pdf)]

・ K. Yoshinaga, S. Sato, R. Sasaki, M. Asada, R. Hori, J. Imagi, Y. Miyazaki, T. Nagai, K. Saito, T. Sano, A. Sasaki, C. Sato, Y. Tsukahara, A. Yamashita, S. Watanabe, and Y. Watanabe. The collaborative study on the enzymatic analysis of positional distribution of short- and mediumchain fatty acids in milk fat using immobilized Candida antarctica lipase B. J. Oleo Sci. 65, 291-302 (2016). [Paper (PDF)]

2015

・ F. Beppu, M. Asanuma, Y. Kawamura, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, S. Kasatani, K. Nagao, A. Kubo, J. Kanda, and N. Gotoh. Trans-octadecenoic acid positional isomers have different accumulation and catabolism properties in mice. J. Oleo Sci. 64, 1159-1167(2015)[Paper (pdf)]

・ Y. Watanabe, S. Sato, M. Asada, T. Arishima, Y. Iida, J. Imagi, K. Saito, T. Sano, A. Sasaki, R. Sasaki, C. Sato, T. Shibuya, Y. Tsukahara, T. Nagai, T. Fukazawa, R. Hori, R. Homma, Y. Miyazaki, A. Yamashita, K. Yoshinaga, and S. Watanabe. Enzymatic analysis of positional distributions in triacylglycerols by 1(3)-selective transesterification with Candida antarctica lipase B: a collaborative study. J. Oleo Sci. 64, 1193-1205 (2015). [Paper (PDF)]

・ T. Nagai, N. Watanabe, K. Yoshinaga, H. Mizobe, K. Kojima, I Kuroda, Y. Odanaka, T. Saito, F. Beppu, and N. Gotoh. Abundances of triacylglycerol positional isomers and enantiomers comprised of a dipalmitoylglycerol backbone and short- and medium-chain fatty acids in bovine milk fat. J. Oleo Sci. 64, 943-952 (2015). [Paper (pdf)]

・ R. Suo, H. Li, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, K. Nagao, F. Beppu, and N. Gotoh. Generation of tetracosahexaenoic acid in benthic marine organisms. J. Oleo Sci. 64, 721-727 (2015). [Paper (pdf)]

・ K. Yoshinaga, Y. Kawamura, T. Kitayama, T. Nagai, H. Mizobe, K. Kojima, Y. Watanabe, S. Sato, F. Beppu, and N. Gotoh. Regiospecific distribution of trans-octadecenoic acid positional isomers in triacylglycerols of partially hydrogenated vegetable oil and ruminant fat. J. Oleo Sci. 64, 617-624 (2015). [Paper (pdf)]

・ F. Beppu, K. Konno, T. Kawamatsu, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, H. Watanabe, and N. Gotoh. Comparison of catabolic rates of 13C-labeled palmitic acid bound to the alpha and beta positions of triacylglycerol using CO2 expired from mice. Eur. J. Lipid Sci. Technol. 117, 718-723 (2015). [Abstract]

・ K. Yoshinaga, K. Sasaki, H. Watanabe, K. Nagao, N. Inoue, B. Shirouchi, T. Yanagita, T. Nagai, H. Mizobe, K. Kojima, F. Beppu, and N. Gotoh. Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice. J. Nutr. Biochem. 26, 57-63 (2015). [Abstract]

2014

・ K. Nagao, K. Nakamitsu, H. Ishida, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, T. Yanagita, F. Beppu, and N. Gotoh. A comparison of the lipid-lowering effects of four different n-3 highly unsaturated fatty acids in HepG2 cell. J. Oleo Sci. 63, 979-985 (2014). [Paper (pdf)]

・ Y. Watanabe, S. Sato, S. Sera, C. Sato, K. Yoshinaga, T. Nagai, R. Sato, H. Iwasaka, and T. Aki. Enzymatic analysis of positional distribution of fatty acids in solid fat by 1,3-selective transesterification with Candida antarctica lipase B. J. Am. Oil Chem. Soc. 91, 1323-1330 (2014). [Abstract]

・ K. Yoshinaga, M. Asanuma, H. Mizobe, K. Kojima, T. Nagai, F. Beppu, and N. Gotoh. Characterization of cis- and trans-octadecenoic acid positional isomers in edible fat and oil using gas chromatography-flame ionization detector equipped with high polar ionic liquid capillary column. Food Chem. 160, 39-45 (2014). [Abstract]

・ 吉永 和明, 後藤 直宏. 【総説】トランス脂肪酸位置異性体分析技術の進展, ミルクサイエンス 63, 71-80 (2014). [Review (pdf)]

2013

・ T. Nagai, Y. Matsumoto, Y. Jiang, K. Ishikawa, T. Wakatabe, H. Mizobe, K. Yoshinaga, K. Kojima, I. Kuroda, T. Saito, F. Beppu, and N. Gotoh. Actual ratios of triacylglycerol positional isomers and enantiomers comprising saturated fatty acids and highly unsaturated fatty acids in fish and marine mammals. J. Oleo Sci. 62, 1009-1015 (2013). [Paper (pdf)]

・ K. Yoshinaga, M. Asanuma, C. Xu, H. Mizobe, K. Kojima, T. Nagai, F. Beppu, and N. Gotoh. Resolution behavior of cis- and trans-octadecenoic acid isomers by AOCS official method using SP-2560 column. J. Oleo Sci. 62, 781-788 (2013). [Paper (pdf)]

・ F. Beppu, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, and N. Gotoh. Quantification of triacylglycerol molecular species in cocoa butter using high-performance liquid chromatography equipped with nano quantity analyte detector. J. Oleo Sci. 62, 789-794 (2013). [Paper (pdf)]

・ N. Gotoh, T. Nagai, K. Yoshinaga, H. Mizobe, and H. Watanabe. Comparison of catabolic rates of fatty acids using stable isotope and isotope-ratio mass spectrometry. Lipid Tech. 25, 110-112 (2013)[Abstract]

・ K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, and N. Gotoh, Simple method for the quantification of milk fat content in foods by LC-APCI-MS/MS using 1,2-dipalmitoyl-3-butyroyl-glycerol as an indicator. J. Oleo Sci. 62, 115-121 (2013). [Paper (pdf)]

2012

・ R. Shibata, N. Gotoh, A. Kubo, J. Kanda, T. Nagai, H. Mizobe, K. Yoshinaga, K. Kojima, H. Watanabe, and S. Wada. Comparison of catabolism rate of fatty acids to carbon dioxide in mice. Eur. J. Lipid Sci. Technol. 114, 1340-1344 (2012).[Abstract]

・ N. Gotoh, Y. Matsumoto, T. Nagai, H. Mizobe, K. Yoshinaga, K. Kojima, I. Kuroda, Y. Kitamura, T. Shimizu, H. Ishida, and S. Wada. Actual ratio of triacylglycerol positional isomers in milk and cheese. J. Oleo Sci. 61, 173-180 (2012). [Paper (pdf)]

2011

・ T. Nagai, N. Gotoh, H. Mizobe, K. Yoshinaga, K. Kojima, Y. Matsumoto, and S. Wada. Rapid separation of triacylglycerol positional isomers binding two saturated fatty acids using octacocyl silylation column. J. Oleo Sci. 60, 345-350 (2011). [Paper (pdf)]